A bill to address national security threats and vulnerabilities that could undermine economic recovery and financial markets.

Economic Security Defense Act of 2010 - Establishes a Security Threats to Financial Markets and Economic Recovery Commission to examine and report to Congress on security threats and vulnerabilities to the U.S. economic recovery and financial markets.

Requires the Commission to make legislative recommendations to Congress and the President designed to address: (1) potential threats to financial markets and economic recovery from both state and non-state actors; (2) vulnerabilities in financial markets that could be exploited and would result in major economic implications; (3) the divide between national security and economic concerns; and (4) national security vulnerabilities associated with current federal debt levels.