Visa Waiver Program Updated Framework and Enhanced Security Act of 2010

Visa Waiver Program Updated Framework and Enhanced Security Act of 2010 - Amends the Immigration and Nationality Act regarding the visa waiver program to: (1) authorize the Secretary of Homeland Security (DHS), in consultation with the Secretary of State, to designate program countries; (2) replace visa refusal rates with visa overstay rates in determining program participation; (3) set a maximum 3% visa overstay rate for program countries; (4) require an annual program compliance report to Congress; and (5) revise probationary status and program termination provisions.

Directs the Comptroller General to review the Secretary of Homeland Security's methods for: (1) tracking aliens entering and exiting the United States; and (2) detecting visa overstays.

Requires: (1) program countries to have agreements in place to share information on lost and stolen passports within 180 days of enactment of this Act; and (2) DHS to make information on all aliens who have overstayed their visas available electronically to state and local law enforcement agencies.