United States Nuclear Fuel Management Corporation Establishment Act of 2010

United States Nuclear Fuel Management Corporation Establishment Act of 2010 - Amends the Atomic Energy Act of 1954 to establish the United States Nuclear Fuel Management Corporation.

Authorizes the Corporation to: (1) implement integrated spent nuclear fuel management consistent with federal policy on a self-sustaining basis through the use of a spent nuclear fuel management enterprise that will eliminate the need for federal funding; and (2) assume responsibility for the activities, obligations, and use of resources of the federal government with respect to spent nuclear fuel management.

Establishes in the Treasury the United States Nuclear Fuel Management Corporation Fund.

Directs the President to appoint a Transition Manager to transfer spent nuclear fuel management obligations, functions, personnel, and funds from the Secretary of Energy to the Corporation.

Designates the Corporation the exclusive marketing agent on behalf of the United States for entering into contracts to provide spent nuclear fuel management and related products and services.