Jean Lafitte National Historical Park and Preserve Boundary Adjustment Act of 2006

Jean Lafitte National Historical Park and Preserve Boundary Adjustment Act of 2006 - Amends the National Parks and Recreation Act of 1978 to: (1) adjust the boundary of the Barataria Preserve Unit of Jean Lafitte National Historical Park and Preserve in Louisiana by increasing the acreage limitation; and (2) authorize the Secretary of the Interior (the Secretary) to acquire any such additional land, water, and interests in land and water by donation, purchase (but only with the owner's consent), transfer from any other federal agency, or exchange.

Requires, with respect to the Bayou aux Carpes Addition and the CIT Tract Addition, any federal land acquired in such Additions to: (1) be transferred without consideration to the administrative jurisdiction of the National Park Service; and (2) any federal land in the Additions that is transferred, be subject to any easements that have been agreed to by the Secretary and the Secretary of the Army. Permits the acquisition of any private land, water, or interests in land and water in the Unit only with the owner's consent.

Modifies and/or eliminates certain provisions related to the acquisition of property within the Unit.

Permits hunting, fishing, and trapping within the Unit, but only as to land, water, or interests in land and water managed by the Secretary. Continues to provide for the designation of zones where, and established periods when, no hunting, fishing, or trapping shall be permitted except for public safety reasons.