Powder Cocaine Sentencing Act of 1999

Powder Cocaine Sentencing Act of 1999 - Amends the Controlled Substances Act to decrease (from five kilograms to 500 grams, and from 500 to 50 grams) the amounts of a mixture or substance containing a detectable amount of coca leaves, cocaine, ecgonine, or compounds thereof (cocaine powder) the manufacture, distribution, or possession of which is punishable by specified penalties under the Act. Makes the same changes in amounts with respect to violations of the Controlled Substances Import and Export Act.

Directs the U.S. Sentencing Commission to promulgate or amend sentencing guidelines to reflect the amendments made by this Act.