Tijuana River Valley Estuary and Beach Sewage Cleanup Act of 2000

Tijuana River Valley Estuary and Beach Sewage Cleanup Act of 2000 - Authorizes and directs the U.S. section of the International Boundary and Water Commission, United States and Mexico, subject to the negotiation and conclusion of a new Treaty Minute pursuant to the Treaty for the Utilization of Waters of the Colorado and Tijuana Rivers and of the Rio Grande or the amendment of Treaty Minute 283, to provide for the secondary treatment of up to 50 million gallons per day (mgd) in Mexico of: (1) effluent from the South Bay International Wastewater Treatment Plant (IWTP) if such treatment is not provided for at a U.S. facility; and (2) additional sewage emanating from the Tijuana River area, Mexico.

Authorizes the Commission, subject to the results of the comprehensive plan developed under this Act revealing a need for additional secondary treatment capacity in the San Diego-Tijuana border region (border region) and recommending the provision of such capacity in Mexico, to provide up to an additional 25 mgd of such capacity for the above-described treatment.

Requires the Administrator of the Environmental Protection Agency to develop a comprehensive plan with stakeholder involvement to address the transborder sanitation problems in the border region.

Permits the Commission, upon conclusion of a new Treaty Minute or the amendment of Treaty Minute 283, to enter into a fee-for-services contract with the owner of the Mexican Facility (proposed wastewater treatment facility to be constructed within Mexico for treating sewage flows generated within Mexico, which flows impact U.S. and Mexican surface waters, health, and safety) to carry out the secondary treatment requirements of this Act. Requires the Inspector General of the Department of State to monitor and report to Congress on such contract.

Requests the Secretary of State to give the highest priority to the negotiation and execution of a new Treaty Minute or a modification of Treaty Minute 283 in order that the other provisions of this Act to address river and ocean pollution in the border region may be implemented as soon as possible. Requests the Secretary to initiate such negotiations with Mexico. Requires the new or modified Treaty Minute to be subject to the provisions of the National Environmental Policy Act of 1969.

Authorizes appropriations.